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While this early research was done with animals, the results are promising
What we are asking OPM to do: End any requirement or pressure that effectively mandates WEGOVY and/or SAXENDA as the default or sole GLP1 option for weight management or related indications on all plans that offer GLP1s
Molecules used in chronic weight loss studies were generated by Amgen as previously described and dosing regimens for each molecule were established by previously published pharmacokinetic and pharmacodynamic studies: mGIPR-Ab (25 mg kg 1 every 6 days) 17 , dulaglutide (0.3 mg kg 1 every 3 days) 17 and mGIPR-Ab/P1 or mGIPR-Ab/P3 (1.5 mg kg 1 every 6 days) 16
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